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[The CIVIS Newsroom ](https://civis.eu/el/the-civis-newsroom) 2. UofG-lead research team tracks new ways to tackle tuberculosis transmission in Africa UofG-lead research team tracks new ways to tackle tuberculosis transmission in Africa ======================================================================================= CIVIS Highlights 7 Οκτωβρίου 2024 ZAMSA-TB is the name of the study searching for new methods to understand recent tuberculosis (TB) transmission in Africa, target interventions such as new vaccines, and measure their effectiveness. The international team of researchers, awarded with the *[Wellcome Discovery Award ](https://wellcome.org/grant-funding/schemes/discovery-awards)(*£2.9 million/3.5 million €), is led by Professor Peter MacPherson, from the University of Glasgow's School of Health & Wellbeing. The project will also support the development of a group of world-leading African scientists and epidemiologists equipped to tackle TB. ![](/storage/files/tbc.jpg) ©UofG Tuberculosis (TB) is the leading infectious killer globally. In Africa, TB is becoming increasingly concentrated in densely populated cities, often driven by HIV infection, and poor, crowded living conditions. New TB drugs, vaccines, and diagnostics are now being tested in Africa, but methods for measuring their impact on public health are lacking. > *If the bold aims of this project are successful, we anticipate that the impact could be transformative for efforts to end TB, and might even be used for other infections targeted for elimination. We hope that our methods will guide better-targeted screening and prevention interventions and discover new methods to evaluate the population impact of new TB vaccines, screening, and preventive interventions”,* Professor MacPherson says. The researchers will focus their study on three countries - Malawi, South Africa, Zambia - that are priority sites for future TB vaccine roll-out. The team aims to discover new epidemiological methods to measure recent population patterns of TB transmission based on blood tests of young aged children attending primary clinics in busy cities. By modelling patterns of TB infection at high spatial resolution and over time, they will investigate the potential for this new approach to give rapid, accurate insights into the effectiveness of new TB interventions – such as vaccines – against transmission. A major public health challenge ------------------------------- While huge strides have been made towards its elimination, TB remains a major public health challenge across the world, but some regions such as Africa are disproportionately affected, > *Our project study has the potential to reshape how we understand and track TB transmission and evaluate interventions against it. The tools and methods we develop could provide a generalisable global framework to help us reach the finish line of ending TB. We are excited about the south-to-south knowledge transfer and capacity development that will emanate from the project”,* says Dr Kwame Shanaube, from ZAMBART, Zambia. Dr Lele Rangaka, from the Institute for Global Health, University College London, and University of Cape Town, underlines *the opportunity for training and developing the next cohort of leaders in TB research, while d*r James Chirombo, from the Malawi-Liverpool-Wellcome Programme, sees > *an excellent opportunity towards ending TB transmission in a setting with rapid population growth and urbanisation that has led to informal overcrowded settlements. Coupled with a high HIV burden, these conditions continue to provide an enabling environment for continued transmission. This project will allow us to find hidden hotspots cost effectively for better control of TB infections*”. The prestigious *Wellcome Discovery Award* scheme provides funding for internationally leading researchers and teams from any discipline who want to pursue bold and creative research ideas to deliver significant shifts in understanding that could improve human life, health and wellbeing. **Find out more from the full, [original story](https://www.gla.ac.uk/news/headline_1110995_en.html).** ### Other stories this month: *[BIP, BIP, Hooray! Guest article from MSCA fellow Anna Zech](https://civis.eu/en/get-informed/news/guest-blog-post-bip-bip-hooray)* *[Power-to-vitamins: microbes produce folate from simple basic ingredients, say researchers from Tübingen](https://civis.eu/en/get-informed/news/power-to-vitamins-microbes-produce-folate-from-simple-basic-ingredients-say-researchers-from-tubingen)* *[UB-trained Romanian high schoolers have dominated the Olympiads this summer](https://civis.eu/en/get-informed/news/ub-trained-romanian-high-schoolers-have-dominated-the-olympiads-this-summer)* *[European Universities alliances advocate to include third-country HEIs in Erasmus Without Papers](https://civis.eu/en/get-informed/news/european-universities-alliances-advocate-to-include-third-country-heis-in-erasmus-without-papers)* Related news ------------ - [ ![](https://civis.eu/storage/files/the-800x600.jpg?token=093ed83bda03945717bc4b6f81b3ec67)Improvements for UofG in THE Subject Rankings 2026 CIVIS Highlights 26 Φεβρουαρίου 2026 ](https://civis.eu/el/the-civis-newsroom/improvements-for-uofg-in-the-subject-rankings-2026) - [ ![](https://civis.eu/storage/files/compostable-circuits-800x600.jpg?token=a19526df4708995e83863edd1dfe37f5)Compostable circuits could slash environmental impact of electronics CIVIS Highlights 22 Ιανουαρίου 2026 ](https://civis.eu/el/the-civis-newsroom/compostable-circuits-could-slash-environmental-impact-of-electronics) - [ ![](https://civis.eu/storage/files/bird-flu-800x600.jpg?token=d5aae32131e7d7d8e26444a1feeb53e6)Scientists track adaptation of bird flu in dairy cattle CIVIS Highlights 18 Δεκεμβρίου 2025 ](https://civis.eu/el/the-civis-newsroom/scientists-track-adaptation-of-bird-flu-in-dairy-cattle) [Ανακαλύψτε όλες μας τις ιστορίες](https://civis.eu/el/the-civis-newsroom) [ BIP, BIP, Hooray! Guest article from MSCA fellow Anna Zech ](< https://civis.eu/el/the-civis-newsroom/guest-blog-post-bip-bip-hooray >) [ Power-to-vitamins: microbes produce folate from simple basic ingredients, say researchers from Tübingen ](< https://civis.eu/el/the-civis-newsroom/power-to-vitamins-microbes-produce-folate-from-simple-basic-ingredients-say-researchers-from-tubingen >) ![CIVIS – Europe’s Civic University Alliance](https://civis.eu/build/assets/civis-CCpvK1nT.svg) ------------------------------------------------------------------------------------------------- Europe’s Civic University Alliance ![Co-funded by the European Union](https://civis.eu/build/assets/co-funded-by-the-european-union-DSKLW1us.png)Views and opinions expressed do not necessarily reflect those of the European Union or the European Education and Culture Executive Agency (EACEA). 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